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· The price of directtoconsumer genetic testing ranges from under a hundred dollars to several thousand dollars. The cost depends on how many genetic variations are analyzed (and it will cost more if whole genome or whole exome sequencing is used), how extensive the interpretation of results is, and whether other products, programs, or services are included.
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· In some cases though, screening for low prevalence diseases is also cost effective, if the cost of screening is less than the cost of care if the disease is not detected early. For example, phenylketonuria (PKU) is a rare disease but has very serious longterm consequences if left untreated.
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· The estimated cost for generating that initial 'draft' human genome sequence is ~ 300 million worldwide, of which NIH provided roughly 5060%. The HGP then proceeded to refine the 'draft' and produce a 'finished' human genome sequence (as described above), which was achieved by 2003.